What to expect after immunisation: young people

This information tells you about the common side effects of immunisations that might occur in young people from 12 to 18 years of age.

This information is to be used as a guide only. If you’re worried, get advice from a health professional or phone NHS 24 on 111.

After immunisations given to young people

The most common side effects are at the site where the injection was given. These include:

  • swelling
  • redness
  • stinging
  • itching
  • bruising
  • tenderness
  • a small painless lump

These symptoms usually pass within a couple of days. You don’t need to do anything about them.

Phone your GP practice if:

  • you’re concerned about any side effects
  • you have a temperature of 38°C or above for more than 48 hours
  • you have a temperature of 39°C or above at any time

Tell your GP practice about your vaccination. This is so they can assess you properly.

If your GP practice is closed, call NHS 24 on 111.

After the HPV vaccination

Possible common side effects of the HPV immunisation can include:

  • headache
  • nausea
  • fatigue
  • dizziness
  • fever

After the MenACWY vaccine

Possible common side effects after the MenACWY vaccine include:

  • fever
  • headache
  • muscle aches
  • generally feeling unwell

After the DTP vaccination

Possible common side effects of the DTP immunisation can include:

  • feeling or being sick
  • dizziness
  • fever
  • headache

How to treat a fever in children

After the MMR vaccination

MMR is made up of 3 different vaccines (measles, mumps and rubella) which can cause reactions at different times after the injection.

Side effects after 6 to 11 days after MMR vaccination

Possible common side effects 6 to 11 days after MMR vaccination include:

  • fever
  • rash

Side effects at 2 to 3 weeks after MMR vaccination

Possible common side effects around 2 to 3 weeks after the MMR vaccination include:

  • swollen glands around the neck, cheeks and jaw
  •  a brief rash
  • a slightly raised temperature 

On rare occasions, sore or stiff joints may develop 2 to 3 weeks after MMR vaccination.

Where can I report suspected side effects?

You can report suspected side effects of vaccines and medicines through the Yellow Card Scheme.

This can be done by:

  • visiting the Yellow Card Scheme website
  • phoning the free Yellow Card hotline on 0800 731 6789 (available Monday to Friday, 9am to 5pm)

Vaccine Safety Net Member

Public Health Scotland is a proud member of the Vaccine Safety Net and partners with NHS inform to provide reliable information on vaccine safety.

The Vaccine Safety Net is a global network of websites, evaluated by the World Health Organization, that provides reliable information on vaccine safety.

More about the Vaccine Safety Net

Further information and other languages/formats

More information on vaccines for young people can be found in these leaflets, available in multiple languages and formats:

Last updated:
02 December 2025

Search for immunisation services